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DUROESIC^(R) is a transdermal patch providing continuous systemic delivery of fentanyl, a potent opioid analgesic for 72 hours. A retrospective Drug Use (DUE) study on fentanyl Transdermal Therapeutic System(TTS) was conducted. The charts of 50 patients, hospitalized at St. Mary´s Hospital from March 1. 1996 to May 31. 1996 and applied fentanyl TTS, were reviewed. The procedure collaborated DUS criteria for fentanyl TTS established by American Journal of health-system pharmacists(AJHP) and manufacturer´s guideline. The following information was gathered for patient; indication for use, initial dosage, and dosage interval. As a result, 46 patients(96％) met the criteria for indication of use, 30 patients met the criteria for initial dosage conforms, and 42 patients met criteria for dosage interval. Adverse effects, constipation(44％), nausea/vomiting(23％), respiratory depression (13%), etc, were observed. This study suggests the education for TTS dosage form needs to be provided to medical team.
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